The Nautilus Delta is a Wireless electrocardiogram system based Catheter Guiding System designed byRomedex.

What is the Nautilus Delta by Romedex?

The Nautilus DeltaTM system by Romedex consists of the following elements.

  • A single use sterile ECG extension cable
  • non-sterile ECG cable
  • patient module (ECG data acquisition and processing plus integrated remote control)
  • mobile medical application running on any mobile platform which complies with the minimum requirements.

Nautilus DeltaTM provides real-time catheter tip location information by using the patient’s cardiac electrical activity (ECG). Medical professionals can then use this information to position any commercially available central venous catheter at or around the cavo-atrial junction (CAJ). Nautilus Delta supports navigation of central venous catheters from the vascular access point towards the CAJ by computing and displaying a navigation signal.

Nautilus Delta also displays on its graphical user interface the surface (skin) ECG signal, a marker identifying the R-peak, and the patient’s heart rate. In order to obtain intravascular ECG information at the tip (distal end) of a catheter, a stylet or a guidewire inserted in the catheter connects to Nautilus Delta patient module via the sterile Nautilus adaptor (the sterile ECG extension cable).

Benefits of the Nautilus Delta by Romedex

The Nautilus Delta, a new wireless system, has many advantages of delivering IC-ECG optimal clinical performance compared to ECG monitors. It is light and easy to carry, subsequently making it flexible and easier for bedside insertion and patient accessibility.

The Nautilus Delta has a major advantage in that it is located on a portable device with easy access to data storage and printing. This also allows for maximum documentation and other practical uses.

Features and Technical Details of the Nautilus Delta by Romedex


The intracavitary ECG method (IC-ECG) wad adopted in clinical practice to assess the central tip location of venous access devices (VAD). We report our preliminary experience with a new wireless system specifically dedicated to the IC-ECG (Nautilus Delta (aka Handy), Romedex). This consists of a small box connected to the ECG cables, sending data to a smartphone or a tablet by bluetooth technology.
The phone/tablet includes a software application which displays both the surface and intracavitary ECG.


The IC-ECG method is performed according to the standard procedure. The freeze function makes the identification of the peak of the P wave (corresponding to the cavo-atrial junction) easy. This feature is available from the box or from the phone/tablet.


The new device was adopted for tip location in 207 central VADs (154 PICCs, 49 ports, 2 short term CVCs and 2 cuffed-tunneled catheters) placed after cannulation of different veins (96 basilic, 41 brachial, 57 axillary-subclavian, 6 internal jugular, 7 brachio-cephalic) . The P wave was evident on basal ECG in all patients. A P wave peak was easily detected in all patients. In 36 patients, the procedure was performed with both a dedicated ECG device (Nautilus, Romedex) and with Handy. There were no differences in terms of performance.

Discussion and conclusions:

This new wireless system for IC-ECG had an optimal clinical performance in terms of applicability and feasibility. Transmission of the data to the moveable device by bluetooth simplified the wire connections. The following are some potential advantages over other ECG monitors. The system is light and easy to carry – making it ideal for bedside insertion. The same professional inserting the VAD operates the ECG. There is no risk of electrical hazard. The ECG uses a personal portable device, allowing easy storage of data and easy printing for documentation.

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